Cancer in Functional and Integrative MedicineE-book · ENOX2, metabolic therapy and protocols
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Cover of the e-book Cancer in Functional and Integrative Medicine: prevention, nutraceuticals, ENOX2, metabolic therapy and protocols.

PDF e-book · 190 pages · Dr. Carlos Rogerio

Cancer in Functional and
Integrative Medicine

Cancer takes years to show up on an imaging exam. ENOX2, a protein that disappears from the normal adult cell and reappears in cancer, was detected in the blood 4 to 10 years before diagnosis in mesothelioma. This e-book starts from that window and delivers what to do in it: the protocols to inhibit ENOX2, the GKI-guided ketogenic diet and nutraceuticals with dose, evidence and interactions with chemotherapy and radiotherapy, always as adjuncts.

  • ENOX2: early detection and inhibition protocols
  • Metabolic therapy: GKI-guided ketosis, insulin and mTOR
  • Nutraceuticals, herbal medicines and drugs with dose and evidence

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Intended for health professionals. Patients and caregivers can also buy it.

01Why this e-book exists

What almost no one tells you
about cancer, diet and supplements.

In groups and in clinics, integrative oncology often turns into a list of supplements and a carb-free diet. These are six points the e-book takes apart, each with the evidence label for what is claimed and the module where the topic is covered in detail.

  • 01Module 12

    "Cancer begins when it shows up on an exam"

    It does not. According to Morré and Morré, fewer than 20% of cancers are diagnosed at a localized stage. ENOX2, a protein on the surface of the neoplastic cell that is shed into the blood, opens another window: the e-book shows the ONCOblot, the tissue of origin each pattern points to and the studies with the National Cancer Institute serum panels.

  • 02Module 12

    "A ketogenic diet is just cutting carbs"

    Without measuring, there is no way to know whether the diet has reached the therapeutic zone. What counts is the GKI, the ratio between glucose and ketones in the blood, with a target of 2.0 or less: in the e-book's protocols, a ketogenic diet without GKI measurement is not considered treatment. And urine strips are not suitable for the calculation.

  • 03Module 12

    "Green tea against cancer means EGCG capsules"

    The only regimen with a published outcome in humans used decaffeinated green tea powder with Capsicum powder, in a 25:1 ratio, several times a day, including at night. And concentrated EGCG above 800 mg a day is associated with increased transaminases.

  • 04Module 6

    "Antioxidants always protect the patient"

    For Felippe Jr., in established cancer, antioxidants used as medication protect the tumor cell and reduce the efficacy of chemotherapy and radiotherapy. CFM Resolution No. 2.004/2012, from Brazil's Federal Council of Medicine, prohibits antioxidants that interfere with these treatments. The e-book shows what to review and the exceptions the book itself allows.

  • 05Modules 6 and 7

    "Whey, glutamine and tryptophan help with recovery"

    The author of the reference work contraindicates all three in the cancer patient: whey because it is a glutathione precursor and raises insulin and IGF-1, glutamine because "glutamine is not given to cancer patients" and tryptophan, "formally contraindicated in gliomas".

  • 06Module 16

    "Routine medications do not interfere with cancer"

    For Felippe Jr., drugs that are "apparently harmless and routinely prescribed" can be very harmful to the cancer patient, from calcium channel blockers to anxiolytics. And there are practical interactions: "Do not use paroxetine together with tamoxifen, as it decreases the latter's effects".

The e-book does not replace cancer treatment or the assessment of each patient. Everything it describes is integrative and adjuvant, carried out together with the oncologist, and it separates what has studies behind it from what is the author's opinion.

02What you get

From early detection to protocol,
with the evidence for each step.

The terms of the cover subtitle, delivered in dose tables, flowcharts and monographs.

The window for intervention

For the author of this ebook, conventional detection comes too late and takes away the patient's chance of early treatment. A marker that identifies the tumor years before symptoms makes it possible to act when the tumor burden is minimal, with low-toxicity interventions [AE].

How the boxes appear in the e-book (module 12)
01
Part 4 · module 12

ENOX2: early detection and inhibition protocols

The protein that sets the neoplastic cell apart from the normal one, and what to do when it shows up.

  • Why inhibition is selective: ENOX2 is absent from the normal adult cell, and continuous blockade for 48 to 72 hours drives the neoplastic cell into apoptosis
  • The ONCOblot: each cancer's pattern in the blood, the tissue of origin and the detection limit, a tumor of about 0.8 mm
  • The Capsol-T trial: of the 32 positive participants who repeated the test, 30 turned ONCOblot-negative [CT]
  • Protocols A to E: Capsol-T as in the study, the compounded formula, the approach for those who remain positive and the high dose with transaminase monitoring
  • The management flowchart, the baseline tests and the interactions, such as green tea with bortezomib
02
Modules 1, 2, 5, 12 and 14

Metabolic therapy: GKI-guided ketosis, insulin and mTOR

The diet acts on the terrain that feeds the tumor, and the GKI shows whether it is working.

  • Seyfried's metabolic theory of cancer and the press-pulse strategy
  • The GKI: the formula, the therapeutic ranges and how to measure it in capillary blood, with AnameLab's GKI and HOMA-2 calculators
  • The GKI-guided ketogenic protocol: carbohydrates, ratio, protein, MCT, fasting and monitoring
  • Insulin and mTOR: HOMA, the fasting insulin target of 5 to 6 mU/mL and what stimulates mTOR in the tumor
  • When not to induce ketosis, and Felippe Jr.'s smart diet with phases, targets, menu, recipes and the Budwig diet
03
Parts 3 to 5 · modules 7 to 11, 15 to 17 and 19

Nutraceuticals, herbal medicines and drugs with dose and evidence

Every agent in the same template: mechanism, evidence, dose, contraindications and interactions.

  • Nutrients and bioactive compounds: omega-3, melatonin, vitamin D, curcumin, green tea, sulforaphane and fucoidan, among others
  • Herbal medicines, from Boswellia to Reishi, and the antimicrobial plants in the author's strategy
  • Repurposed drugs: metformin, DCA, low-dose naltrexone, mebendazole, cimetidine, ivermectin and fenbendazole
  • The formulas from ch. 127 of the reference work, with components, dosage and the doses that call for special caution
  • Common drugs to avoid, the chart of interactions with chemotherapy and radiotherapy and the molecular map that cross-references each tumor pathway with the agents
03Contents

190 pages in five parts.

From the neoplastic cell to the protocols: foundations, prevention and nutrition, the therapeutic arsenal, the ENOX2 strategies and metabolic therapy, and a supplement with a molecular map, frequently asked questions and a glossary. Every claim carries its evidence label.

Part 1p. 8

Foundations

Functional view of cancer, pathophysiology of the neoplastic cell, causes and clinical and laboratory investigation.

  1. Mod. 1Cancer from a functional perspectivep. 9
  2. Mod. 2Functional pathophysiology: the secrets of the neoplastic cellp. 15
  3. Mod. 3Causes of cancer and functional clinical and laboratory investigationp. 28

Part 2p. 35

Prevention, Nutrition and Oxidation

Prevention, the smart diet and the rule on antioxidants during cancer treatment.

  1. Mod. 4Cancer prevention: diet, physical activity, sun and saltp. 36
  2. Mod. 5Smart carcinostatic and anticarcinogenic dietp. 43
  3. Mod. 6Antioxidants, intracellular oxidation and cancer treatmentp. 49

Part 3p. 55

Therapeutic Arsenal

Monographs on nutrients, bioactive compounds, herbal medicines, repurposed drugs and physical and parenteral therapies.

  1. Mod. 7Nutrients, vitamins, minerals and hormonesp. 56
  2. Mod. 8Bioactive compounds and nutraceuticalsp. 70
  3. Mod. 9Herbal medicines in cancerp. 84
  4. Mod. 10Repurposed drugsp. 97
  5. Mod. 11Physical and parenteral therapiesp. 113

Part 4p. 120

Strategies, Protocols and Safety

Early detection and ENOX2, metabolic therapy, infections and toxic metals, strategies by molecular target, the author's formulas, drugs to avoid, interactions and clinical cases.

  1. Mod. 12Early detection, ENOX2 and metabolic therapyp. 121
  2. Mod. 13Chronic infections, antimicrobials and toxic metalsp. 129
  3. Mod. 14Strategies by molecular targetp. 135
  4. Mod. 15General therapeutic strategy and the author's formulasp. 143
  5. Mod. 16Common drugs to avoid in the cancer patientp. 150
  6. Mod. 17Interactions and safety: consolidated chartp. 155
  7. Mod. 18Clinical cases: summary by tumor typep. 159

Part 5p. 166

Advanced Supplement

Integrative molecular map, frequently asked questions, glossary and bibliographic references.

  1. Mod. 19Integrative molecular mapp. 167
  2. Mod. 20Frequently asked questionsp. 169
  3. Mod. 21Glossary of abbreviations and termsp. 172
  4. Mod. 22Referencesp. 178

Evidence levels · Table 5

[MA]
Meta-analysis or systematic review
[RCT]
Randomized controlled trial
[CT]
Non-randomized clinical trial
[OBS]
Observational or epidemiological study in humans
[CR]
Case report or case series
[PC]
Preclinical
[AE]
Author's clinical experience or opinion
04Inside

Browse
before you buy.

Eight of the 190 pages, exactly as they appear in the PDF. Tap a page to enlarge it.

Module 1 · Evidence levels and how to read the dosesPage 14 of 190
Module 5 · One-day menu and the author's recipesPage 45 of 190
Module 8 · Curcumin monograph, with the dose tablePage 71 of 190
Module 12 · ENOX2 inhibitors and the Capsol-T trialPage 123 of 190
Module 12 · Management flowchart and GKI rangesPage 126 of 190
Module 15 · Formulas from ch. 127, with components and dosagePage 145 of 190
Module 16 · Drugs and substances to avoid according to the authorPage 153 of 190
Module 19 · Molecular map: targets and agents in the e-bookPage 167 of 190
05Who it's for

Written for those who prescribe and for those going through treatment.

The e-book is intended for health professionals, but patients and caregivers can also buy it. The professional finds the dose, the evidence and the interactions of each strategy; patients and those who care for them understand what is being proposed and arrive at the appointment knowing what to ask the oncologist.

Health professionals

Who work in integrative oncology, within the scope of their legal competencies, and need the dose, the evidence and the interactions of each adjuvant strategy.

  • The protocols to inhibit ENOX2, with composition, dosage, monitoring and the management flowchart
  • GKI-guided ketosis, HOMA and the insulin and IGF-I targets
  • Monographs with dose, route, contraindications and timing relative to chemotherapy and radiotherapy
  • Common drugs to avoid, the consolidated interactions and the checklist before starting any protocol

Patients and caregivers

Who wish to understand integrative strategies and discuss them with the team caring for them.

  • What ENOX2 is and what the ONCOblot shows, so you can bring the question to your appointment
  • Why the ketogenic diet needs measurement and supervision, and when it should not be done
  • Why antioxidant supplements, whey and glutamine call for a conversation with the oncologist before use
  • The frequently asked questions in module 20 and the glossary, which explains each abbreviation in plain language

Intended for health professionals. For patients and caregivers, the e-book is a way to understand integrative strategies: it is not a prescription, it does not replace a consultation with a licensed professional, and no cancer treatment or current medication should be stopped or changed on your own.

06Offer

The complete e-book
for $0.

One-time payment. No subscription and no monthly fee.

Cover of the e-book Cancer in Functional and Integrative Medicine: prevention, nutraceuticals, ENOX2, metabolic therapy and protocols.

AuthorDr. Carlos Rogerio@drcarlosanameOctober 2026 edition

What you get
  • 190-page PDF e-book with 22 modules in 5 parts
  • Early detection by ENOX2 and Protocols A to E to inhibit it, with the management flowchart
  • Metabolic therapy: GKI-guided ketosis, HOMA, insulin and mTOR, and the smart diet with a menu and recipes
  • Monographs on nutrients, nutraceuticals and herbal medicines, with dose, route and interactions with chemotherapy and radiotherapy
  • Repurposed drugs, the formulas from the reference work and common drugs to avoid
  • Strategies by molecular target, clinical cases by tumor type and the integrative molecular map
  • 167 tables, 324 scientific references, frequently asked questions and a glossary of abbreviations and terms
PDF pages
190
modules in 5 parts
22
tables
167
scientific references
324
citations with the page of the reference work
933

Every claim carries its evidence label ([MA] [RCT] [CT] [OBS] [CR] [PC] [AE]), and the opinion of the author of the reference work is marked as [AE], kept apart from what has studies behind it. Where a safety warning was missing, the "Caution from this ebook" notes bring what the package insert and official sources say.

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07FAQ

Frequently asked
questions

If yours is not here, write to contato@basefuncional.com.

From ENOX2 to the GKI,
integrative oncology with dose and evidence.

Get the e-book for $0

190 pages, 22 modules and 167 tables, for $0 as a one-time payment.

Intended for health professionals. Integrative and adjuvant strategies: it is not a prescription and does not replace cancer treatment or a consultation with a licensed professional.